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Botulinum toxin is produced primarily by Clostridium botulinum, a spore-forming obligate anaerobe. The toxin targets neurons and mainly causes a flaccid muscle paralysis. The use of botulinum toxin as a biological weapon would most likely take the form of aerosolization or food contamination. This concern has heightened since Iraq's acknowledgement in 1995 of the production of 19,000 L of botulinum toxin, three times the amount needed to annihilate the entire human population Read More...

Tuberculosis For tuberculosis to cause an FUO (Fever of Unknown Origin), it must typically manifest as either disseminated or primarily extrapulmonary disease. Approximately 25% of the time, a tuberculin skin test will be negative in this situation. The diagnosis of extrapulmonary tuberculosis, in particular, can be challenging Read More...