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The incubation period for chlamydial NGU and NGC is usually 1 to 2 weeks, but varies from a few days to several weeks. These infections are commonly asymptomatic, 3 to 10% of sexually active adults having unsuspected chlamydial infection. Longstanding silent infection may be activated by a triggering factor such as acute gonorrhoea
NGU may present with urethral discharge, itchiness, tingling and dysuria. Posterior urethritis may cause frequency and urgency. The discharge may be watery or sticky. A purulent discharge is more likely to be due to gonorrhoea. Meatal inflammation is less conspicuous than in gonococcal urethritis. Persistence or recurrence of urethral symptoms usually without discharge may occur without demonstrable microorganisms.
Spread to the prostate occurs, but acute prostatitis is rare. NGU may progress to epididymitis which is usually unilateral with genital pain, local tenderness and swelling. Sequelae include infertility.
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